Therapeutic Options for the Single Pill Combination of Lisinopril, Amlodipine and Rosuvastatin: a Systematic Review

نویسندگان

چکیده

Aim . To evaluate the effect of taking a single pill combination amlodipine, lisinopril and rosuvastatin on blood pressure (BP) low-density lipoprotein cholesterol (LDL-C) in hypertensive patients with or without severe hypercholesterolemia. Material methods Articles published Russian were selected for analysis. Six articles that met criteria inclusion systematic review found by searching eLibrary database keyword "equamer". The results 5 observational clinical studies presented these articles. effectiveness fixed was assessed mainly changes level systolic diastolic pressure, concentration LDL cholesterol. In addition, effects fixed-dose lisinopril, central aortic its increment index, as well carotid-femoral pulse wave velocity, studied part studies. LDL-C concentration, additional indicators, who had coronavirus infection lung damage one study. Results Evidence from demonstrates efficacy reducing wide range different baseline risk developing cardiovascular complications levels LDL-C. Conclusion data obtained confirm feasibility more frequent prescription practice treatment high moderate diseases, including concomitant

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ژورنال

عنوان ژورنال: Racional?naâ Farmakoterapiâ v Kardiologii

سال: 2022

ISSN: ['2225-3653', '1819-6446']

DOI: https://doi.org/10.20996/1819-6446-2022-08-13